Difference between revisions of "TreP"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[treP]]-[[treA]]-[[treR]]''
+
* '''Operon:''' ''[[treP]]-[[treA]]-[[treR]]'' {{PubMed|8755887}}
  
* '''[[Sigma factor]]:''' [[SigA]]
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8755887}}
  
* '''Regulation:''' repressed by glucose ([[CcpA]])   
+
* '''Regulation:'''  
 +
** induced by trehalose ([[TreR]]) {{PubMed|8755887}}
 +
** repressed by glucose ([[CcpA]])   
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
+
* '''Regulatory mechanism:'''  
 +
** [[TreR]]: transcription repression {{PubMed|8755887}}
 +
** [[CcpA]]: transcription repression  
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 19:19, 31 August 2009

  • Description: trehalose-specific phosphotransferase system, EIIBC component

Gene name treP
Synonyms treB
Essential no
Product trehalose-specific phosphotransferase system, EIIBC component
Function trehalose uptake and phosphorylation
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 49 kDa, 8.555
Gene length, protein length 1410 bp, 470 aa
Immediate neighbours yfkQ, treA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TreP context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU07800

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)
  • Protein family: PTS permease, sucrose permease (Scr) family PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
    • TreR: transcription repression PubMed
    • CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References