Difference between revisions of "FbpC"

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* '''Description:''' small protein, acts as RNA chaperone for frsA <br/><br/>
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* '''Description:''' small protein, acts as RNA chaperone for ''[[fsrA]]'' <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|''fbpC''
 
|''fbpC''
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''mrgC ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || write here
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || write here
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Product''' || small protein, acts as RNA chaperone for frsA
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|style="background:#ABCDEF;" align="center"| '''Product''' || small protein, acts as RNA chaperone for ''[[fsrA]]''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone
 
|style="background:#ABCDEF;" align="center"|'''Function''' || RNA chaperone
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=FbpC FbpC]'''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || xx,x kDa, 9.1
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || xx,x kDa, 9.1
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 87 bp, 29 amino acids
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 87 bp, 29 amino acids
 
|-
 
|-
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ypbR]]'', ''[[ypbQ]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dynA]]'', ''[[bpsB]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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<br/><br/>
 
<br/><br/>
 +
 +
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[acquisition of iron]]}},
 +
{{SubtiWiki category|[[iron metabolism]]}},
 +
{{SubtiWiki category|[[RNA chaperones]]}},
 +
{{SubtiWiki category|[[short peptides]]}}
 +
 +
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[Fur regulon]]}}
  
 
=The gene=
 
=The gene=
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* transcription profile of a ''[[fbpC]]'' mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
  
 
* '''DBTBS entry:''' no entry
 
* '''DBTBS entry:''' no entry
  
 
* '''SubtiList entry:'''
 
* '''SubtiList entry:'''
 +
 +
* '''GEO entry:''' [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] {{PubMed|22389480}}
  
 
=== Additional information===
 
=== Additional information===
 +
 +
  
 
=The protein=
 
=The protein=
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
−
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''
  
−
* '''Localization:'''
+
* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=?&redirect=T ?]
  
 
* '''Structure:'''
 
* '''Structure:'''
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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced upon iron starvation ([[Fur]]) {{PubMed|18697947}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[Fur]]: transcription repression {{PubMed|18697947}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
−
# Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD. (2008) The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.  ''Proc Natl Acad Sci U S A.'' '''Aug 19;105(33):''' 11927-32. [http://www.ncbi.nlm.nih.gov/sites/entrez/18697947 PubMed]
+
<pubmed>18697947 22389480 </pubmed>
−
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed]
+
 
 +
[[Category:short peptide]]

Latest revision as of 11:52, 8 April 2014

  • Description: small protein, acts as RNA chaperone for fsrA

Gene name fbpC
Synonyms mrgC
Essential write here
Product small protein, acts as RNA chaperone for fsrA
Function RNA chaperone
Metabolic function and regulation of this protein in SubtiPathways:
FbpC
MW, pI xx,x kDa, 9.1
Gene length, protein length 87 bp, 29 amino acids
Immediate neighbours dynA, bpsB
Gene sequence (+200bp) Protein sequence
Genetic context
FbpC context.jpg



Categories containing this gene/protein

acquisition of iron, iron metabolism, RNA chaperones, short peptides

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • BsubCyc: ?
  • BsubCyc: ?
  • DBTBS entry: no entry
  • SubtiList entry:

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • BsubCyc: ?
  • BsubCyc: ?
  • Structure:
  • Swiss prot entry:
  • KEGG entry: no entry
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Gregory T Smaldone, Olga Revelles, Ahmed Gaballa, Uwe Sauer, Haike Antelmann, John D Helmann
A global investigation of the Bacillus subtilis iron-sparing response identifies major changes in metabolism.
J Bacteriol: 2012, 194(10);2594-605
[PubMed:22389480] [WorldCat.org] [DOI] (I p)

Ahmed Gaballa, Haike Antelmann, Claudio Aguilar, Sukhjit K Khakh, Kyung-Bok Song, Gregory T Smaldone, John D Helmann
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proc Natl Acad Sci U S A: 2008, 105(33);11927-32
[PubMed:18697947] [WorldCat.org] [DOI] (I p)

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