Difference between revisions of "FlgN"

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* '''Description:''' similar to flagellar protein <br/><br/>
+
* '''Description:''' flagellar filament assembly protein <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || flagellar filament assembly protein
 
|-
 
|-
−
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || flagellar filament assembly
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35420 flgN]
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=FlgN FlgN]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 8.81   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 8.81   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flgK]]'', ''[[flgM]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[flgK]]'', ''[[flgM]]''
 
|-
 
|-
−
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15559&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35420 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35420 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35420 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yvyG_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yvyG_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 +
|-
 +
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvyG_3639787_3640269_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yvyG_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35420]]
 
|-
 
|-
 
|}
 
|}
  
 
__TOC__
 
__TOC__
−
 
+
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 +
<br/><br/><br/><br/>
 
<br/><br/>
 
<br/><br/>
  
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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 
{{SubtiWiki regulon|[[ComK regulon]]}},
 
{{SubtiWiki regulon|[[ComK regulon]]}},
 +
{{SubtiWiki regulon|[[DegU regulon]]}},
 
{{SubtiWiki regulon|[[SigD regulon]]}}
 
{{SubtiWiki regulon|[[SigD regulon]]}}
  
Line 46: Line 55:
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* non-motile cells {{PubMed|24706744}}
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35420&redirect=T BSU35420]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comFABC-yvyF-flgM-yvyG-flgKL.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/comFABC-yvyF-flgM-yvyG-flgKL.html]
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=== Additional information===
 
=== Additional information===
−
 
−
 
−
 
  
 
=The protein=
 
=The protein=
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** essential for flagellar filament assembly, export of hook-filament junction proteins [[FlgK]] and [[FlgL]] {{PubMed|24706744}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
−
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
−
* '''Modification:''' phosphorylation on Tyr-49 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed]
+
* '''Modification:'''  
 +
** phosphorylated on Arg-60 {{PubMed|22517742}}, phosphorylation does not affect the properties of the protein {{PubMed|24706744}}
 +
** phosphorylation on Tyr-49 [http://www.ncbi.nlm.nih.gov/sites/entrez/17218307 PubMed], phosphorylation does not affect the properties of the protein {{PubMed|24706744}}
  
−
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
−
* '''Interactions:'''
+
* '''[[SubtInteract|Interactions]]:'''
  
−
* '''Localization:'''
+
* '''[[Localization]]:'''
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU35420&redirect=T BSU35420]
  
 
* '''Structure:'''
 
* '''Structure:'''
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=Expression and regulation=
 
=Expression and regulation=
 
* '''Operon:'''  
 
* '''Operon:'''  
−
** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
+
** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}}
−
** ''[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
+
** ''[[yvyF]]-[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}}
 +
** ''[[flgM]]-[[flgN]]-[[flgK]]-[[flgL]]'' {{PubMed|21736639}}
 +
 
 +
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvyG_3639787_3640269_-1 flgN] {{PubMed|22383849}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
 
** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}}
 +
** ''[[flgM]]'': [[SigD]] {{PubMed|21736639}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 
** [[ComK]]: transcription activation {{PubMed|8412657}}
 
** [[ComK]]: transcription activation {{PubMed|8412657}}
 +
** ''[[flgM]]'': [[DegU]]-P: transcription activation {{PubMed|21736639}}
  
−
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
−
<pubmed>8412657 8045879 17218307, 15817382 </pubmed>
+
<pubmed>8412657 8045879 17218307, 15817382 22517742 24706744 21736639 24728941 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Latest revision as of 07:13, 15 April 2014

  • Description: flagellar filament assembly protein

Gene name yvyG
Synonyms yviC
Essential no
Product flagellar filament assembly protein
Function flagellar filament assembly
Gene expression levels in SubtiExpress: flgN
Interactions involving this protein in SubtInteract: FlgN
MW, pI 18 kDa, 8.81
Gene length, protein length 480 bp, 160 aa
Immediate neighbours flgK, flgM
Sequences Protein DNA DNA_with_flanks
Genetic context
YvyG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YvyG expression.png















Categories containing this gene/protein

motility and chemotaxis, phosphoproteins

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

  • Locus tag: BSU35420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • essential for flagellar filament assembly, export of hook-filament junction proteins FlgK and FlgL PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
    • phosphorylated on Arg-60 PubMed, phosphorylation does not affect the properties of the protein PubMed
    • phosphorylation on Tyr-49 PubMed, phosphorylation does not affect the properties of the protein PubMed
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

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