Difference between revisions of "Sandbox"

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* '''Description:''' 2-oxoisovalerate dehydrogenase (E1 alpha subunit) <br/><br/>
+
* '''Description:''' 2-oxoisovalerate dehydrogenase (E1 beta subunit) <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''bkdAA''
+
|''bkdAB''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''bfmBAA, bfmB1a, bkd ''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''bfmBAB, bfmB1b, bkd ''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || 2-oxoisovalerate dehydrogenase (E1 alpha subunit)  
+
|style="background:#ABCDEF;" align="center"| '''Product''' || 2-oxoisovalerate dehydrogenase (E1 beta subunit)
(2-oxoisovalerate dehydrogenase alpha subunit) (EC 1.2.4.4)
+
 
 +
(2-oxoisovalerate dehydrogenase beta subunit) (EC 1.2.4.4)
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of branched-chain keto acids
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of branched-chain keto acids
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 36 kDa, 4.778  
+
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 35 kDa, 4.791  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 990 bp, 330 aa  
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 981 bp, 327 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bkdAB]]'', ''[[lpdV]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bkdB]]'', ''[[bkdAA]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein'''
 
|-
 
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:bkdAA_context.gif]]
+
|colspan="2" | '''Genetic context''' <br/> [[Image:bkdAB_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
|-
 
|-
Line 44: Line 45:
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ptb-bcd-buk-lpdV-bkdAABB.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ptb-bcd-buk-lpdV-bkdAABB.html]
  
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10307]
+
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10306]
  
 
=== Additional information===
 
=== Additional information===
Line 73: Line 74:
 
* '''Interactions:'''
 
* '''Interactions:'''
  
* '''Localization:''' Membrane-proximal (Spotty) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
+
* '''Localization:''' Cytoplasm (Homogeneous) [http://www.ncbi.nlm.nih.gov/sites/entrez/16479537 PubMed]
  
 
=== Database entries ===
 
=== Database entries ===
Line 81: Line 82:
 
* '''Swiss prot entry:'''
 
* '''Swiss prot entry:'''
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU24050]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU24040]
  
 
* '''E.C. number:'''
 
* '''E.C. number:'''

Revision as of 18:51, 15 April 2009

  • Description: 2-oxoisovalerate dehydrogenase (E1 beta subunit)

Gene name bkdAB
Synonyms bfmBAB, bfmB1b, bkd
Essential no
Product 2-oxoisovalerate dehydrogenase (E1 beta subunit)

(2-oxoisovalerate dehydrogenase beta subunit) (EC 1.2.4.4)

Function utilization of branched-chain keto acids
MW, pI 35 kDa, 4.791
Gene length, protein length 981 bp, 327 aa
Immediate neighbours bkdB, bkdAA
Hier soll was neues rein
Genetic context
BkdAB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: Cytoplasm (Homogeneous) PubMed

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135-2146. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed