Difference between revisions of "Sandbox"
| Line 1: | Line 1: | ||
| − | * '''Description:''' two-component | + | * '''Description:''' two-component response regulator, regulation of degradative enzyme and genetic competence <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''degU'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''sacU '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''sacU, iep '' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | + | |style="background:#ABCDEF;" align="center"| '''Essential''' || no |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || two-component | + | |style="background:#ABCDEF;" align="center"| '''Product''' || two-component response regulator |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of degradative enzyme and genetic competence | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of degradative enzyme and genetic competence | ||
| + | of genetic competence | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || | + | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.602 |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || | + | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 687 bp, 229 aa |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yviA]]'', ''[[degS]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Hier soll was neues rein''' | ||
|- | |- | ||
| − | |colspan="2" | '''Genetic context''' <br/> [[Image: | + | |colspan="2" | '''Genetic context''' <br/> [[Image:degU_context.gif]] |
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
| Line 43: | Line 44: | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/degSU.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/degSU.html] | ||
| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+ | + | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10393] |
=== Additional information=== | === Additional information=== | ||
| Line 52: | Line 53: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transcription activator of degradative enzyme genes (''[[sacB]]'' and ''[[degQ]]'') and of ''[[comK]]'' expression |
* '''Protein family:''' | * '''Protein family:''' | ||
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
| + | |||
| + | === Genes controlled by DegU === | ||
| + | |||
| + | * '''Activation by DegU:''' ''[[degS]]-[[degU]]'' | ||
| + | |||
| + | * '''Repression by DegU:''' | ||
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 64: | Line 71: | ||
* '''Domains:''' | * '''Domains:''' | ||
| − | * '''Modification:''' phosphorylation | + | * '''Modification:''' phosphorylation by [[DegS]] modulates DNA-binding activity |
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| Line 72: | Line 79: | ||
* '''Interactions:''' [[DegS]]-[[DegU]] | * '''Interactions:''' [[DegS]]-[[DegU]] | ||
| − | * '''Localization:''' | + | * '''Localization:''' |
=== Database entries === | === Database entries === | ||
| Line 80: | Line 87: | ||
* '''Swiss prot entry:''' | * '''Swiss prot entry:''' | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU35490] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
| Line 113: | Line 120: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| − | |||
| − | |||
=Your additional remarks= | =Your additional remarks= | ||
| Line 120: | Line 125: | ||
=References= | =References= | ||
| − | |||
| − | |||
# Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | # Author1, Author2 & Author3 (year) Title ''Journal'' '''volume:''' page-page. [http://www.ncbi.nlm.nih.gov/sites/entrez/PMID PubMed] | ||
Revision as of 17:32, 15 April 2009
- Description: two-component response regulator, regulation of degradative enzyme and genetic competence
| Gene name | degU |
| Synonyms | sacU, iep |
| Essential | no |
| Product | two-component response regulator |
| Function | regulation of degradative enzyme and genetic competence
of genetic competence |
| MW, pI | 25 kDa, 5.602 |
| Gene length, protein length | 687 bp, 229 aa |
| Immediate neighbours | yviA, degS |
| Hier soll was neues rein | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activator of degradative enzyme genes (sacB and degQ) and of comK expression
- Protein family:
- Paralogous protein(s):
Genes controlled by DegU
- Repression by DegU:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation by DegS modulates DNA-binding activity
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced in the presence of ammonium (TnrA)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
