Difference between revisions of "HisD"
| Line 58: | Line 58: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34910&redirect=T BSU34910] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 95: | Line 96: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU34910&redirect=T BSU34910] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KAH 1KAH] (with product and NAD from ''Escherichia coli'', 39% identity, 58% similarity) {{PubMed|11842181}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KAH 1KAH] (with product and NAD from ''Escherichia coli'', 39% identity, 58% similarity) {{PubMed|11842181}} | ||
Revision as of 14:53, 2 April 2014
- Description: histidinol dehydrogenase
| Gene name | hisD |
| Synonyms | |
| Essential | no |
| Product | histidinol dehydrogenase |
| Function | biosynthesis of histidine |
| Gene expression levels in SubtiExpress: hisD | |
| Metabolic function and regulation of this protein in SubtiPathways: hisD | |
| MW, pI | 46 kDa, 4.777 |
| Gene length, protein length | 1281 bp, 427 aa |
| Immediate neighbours | hisB, hisG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34910
Phenotypes of a mutant
Database entries
- BsubCyc: BSU34910
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-histidinol + 2 NAD+ = L-histidine + 2 NADH (according to Swiss-Prot)
- Protein family: histidinol dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU34910
- UniProt: O34651
- KEGG entry: [2]
- E.C. number: 1.1.1.23
Additional information
Expression and regulation
- Sigma factor:
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
