Difference between revisions of "SigB"
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=== Additional information=== | === Additional information=== | ||
| − | + | * mutations in ''[[mtrB]]'', ''[[sigB]]'', ''[[rpoB]]'', and ''[[rpoC]]'' allow ''B. subtilis'' to grow with 4-fluorotryptophan rather than with tryptophan as a canonical amino acid of the genetic code {{PubMed|24572018}} | |
| − | |||
| − | |||
=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 162: | Line 160: | ||
<pubmed> 11544224, 11532142, 11717291, 10482513, 10220166,22174379 </pubmed> | <pubmed> 11544224, 11532142, 11717291, 10482513, 10220166,22174379 </pubmed> | ||
==Other publications== | ==Other publications== | ||
| − | <pubmed>23407164,22511268,22210769 23524614 21979936 8655572,, 3123466, 10369900,3112122, 8468294,8458834, 13129942, 6784117, 12867438, 3100810, 8253681, 12486038, 8764398,3027048, 15342585,17575448, 17586624,23934352, 3016731,11902719,14651641,10503549,15205443,6405278, 10383961, 15805528 6790515 116131, 39767581 19948797 22582280</pubmed> | + | <pubmed>23407164,22511268,22210769 23524614 21979936 8655572,, 3123466, 10369900,3112122, 8468294,8458834, 13129942, 6784117, 12867438, 3100810, 8253681, 12486038, 8764398,3027048, 15342585,17575448, 17586624,23934352, 3016731,11902719,14651641,10503549,15205443,6405278, 10383961, 15805528 6790515 116131, 39767581 19948797 22582280 24572018</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:22, 28 February 2014
- Description: RNA polymerase sigma factor SigB
| Gene name | sigB |
| Synonyms | rpoF |
| Essential | no |
| Product | RNA polymerase sigma factor SigB |
| Function | general stress response |
| Gene expression levels in SubtiExpress: sigB | |
| Interactions involving this protein in SubtInteract: SigB | |
| Metabolic function and regulation of this protein in SubtiPathways: sigB | |
| MW, pI | 29 kDa, 5.418 |
| Gene length, protein length | 792 bp, 264 aa |
| Immediate neighbours | rsbW, rsbX |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
The SigB regulon
The gene
Basic information
- Locus tag: BSU04730
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
- mutations in mtrB, sigB, rpoB, and rpoC allow B. subtilis to grow with 4-fluorotryptophan rather than with tryptophan as a canonical amino acid of the genetic code PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SigB subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P06574
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant: QB5344 (cat), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Bill Haldenwang, San Antonio, USA
- Chet Price, Davis, USA homepage
Your additional remarks
References
Reviews
Control of SigB activity by protein-protein interactions
Identification of the SigB regulon
Other publications
