Difference between revisions of "ComEA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]] | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25590 comEA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComEA ComEA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComEA ComEA] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comEB]]'', ''[[comER]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comEB]]'', ''[[comER]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25590 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25590 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25590 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:comEA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:comEA_context.gif]] | ||
Revision as of 13:21, 13 May 2013
- Description: membrane DNA receptor, plays an important role in the transfer of transforming DNA into the DNA channel and in controlling the rate of DNA uptake
| Gene name | comEA |
| Synonyms | comD |
| Essential | no |
| Product | membrane DNA receptor |
| Function | genetic competence |
| Gene expression levels in SubtiExpress: comEA | |
| Interactions involving this protein in SubtInteract: ComEA | |
| Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation), Protein secretion | |
| MW, pI | 21 kDa, 4.824 |
| Gene length, protein length | 615 bp, 205 aa |
| Immediate neighbours | comEB, comER |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
genetic competence, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25590
Phenotypes of a mutant
- strongly reduced transformation rate PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane, no distinct position PubMed
Database entries
- Structure: 2DUY (from Thermus thermophilus hb8, 37% identity, 60% similarity)
- UniProt: P39694
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159]
[WorldCat.org]
[DOI]
(P p)
Original publications
Additional publications: PubMed
