Difference between revisions of "PabA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate and tryptophan | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of folate and tryptophan | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00750 pabA] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PabA PabA] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PabA PabA] | ||
| Line 26: | Line 26: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pabB]]'', ''[[pabC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pabB]]'', ''[[pabC]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00750 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00750 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00750 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:pabA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:pabA_context.gif]] | ||
Revision as of 11:56, 13 May 2013
- Description: para-aminobenzoate synthase (subunit B)/ anthranilate synthase (subunit II)
| Gene name | pabA |
| Synonyms | trpG, trpX |
| Essential | no |
| Product | para-aminobenzoate synthase (subunit B)/ anthranilate synthase (subunit II) glutamine amidotransferase (subunit B) and anthranilate synthase (subunit II) |
| Function | biosynthesis of folate and tryptophan |
| Gene expression levels in SubtiExpress: pabA | |
| Interactions involving this protein in SubtInteract: PabA | |
| Metabolic function and regulation of this protein in SubtiPathways: Phe, Tyr, Trp, Folate | |
| MW, pI | 21 kDa, 4.782 |
| Gene length, protein length | 582 bp, 194 aa |
| Immediate neighbours | pabB, pabC |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, biosynthesis of cofactors
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00750
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P28819
- KEGG entry: [3]
- E.C. number: 2.6.1.85
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. Mol Microbiol. 2011 81(6): 1459-1473. PubMed:21815947
