lysS

lysS
168

lysyl-tRNA synthetase

Locus
BSU_00820
Molecular weight
57.37 kDa
Isoelectric point
5.03
Protein length
499 aaSequenceBlast
Gene length
1500 bpSequenceBlast
Function
translation
Product
lysyl-tRNA synthetase
Essential
yes
E.C.
6.1.1.6
Synonyms
lysS
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1190 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
88,727  90,226
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
ATP + L-lysine + tRNALys --> AMP + diphosphate + L-lysyl-tRNALys (according to UniProt)
Protein family
Class-II aminoacyl-tRNA synthetase family (according to UniProt)
Structure
3A74 (PDB) (from Geobacillus stearothermophilus, 78.5% identity)
P37477 (AlphaFold)
Localization
cytoplasm (according to UniProt)
Expression and Regulation
Operons
Genes
lysS
Description
PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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lysS

2025-03-25 06:55:18

ghost

71

5ff84b8102b086c431de43008c5bdf2220a940e9

554A7D4A7A5D1CF9E92CF08D5E78AE616950ACBA

Genes
pabB-pabA-pabC-sul-folB-folK-yazB-dusB1-lysS
Description
PubMed
Regulation
translation repressed by tryptophan (MtrB) PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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pabB→lysS

2025-03-09 09:09:51

Jstuelk

120

8c465dd3eec1aaa32d5e91206834f9bb99ef474a

7B9041CE94396BF42D285F7C0EDD3A2544761EEE

References
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Page visits: 3347

Time of last update: 2025-03-31 16:51:23

Author of last update: Jstuelk