Difference between revisions of "RplC"

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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
 
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|23002217,12682299}}
 
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ribosomal protein]] L3 (BL3)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ribosomal protein]] L3 (BL3)
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
  
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
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essential {{PubMed|23002217,12682299}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 
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'''Additional publications:''' {{PubMed|23002217}}
 
<pubmed>17981968,9371452,19154332, 19653700 11948165, 8635744</pubmed>
 
<pubmed>17981968,9371452,19154332, 19653700 11948165, 8635744</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:28, 26 September 2012

Gene name rplC
Synonyms
Essential yes PubMed
Product ribosomal protein L3 (BL3)
Function translation
Gene expression levels in SubtiExpress: rplC
Interactions involving this protein in SubtInteract: RplC
MW, pI 22 kDa, 10.31
Gene length, protein length 627 bp, 209 aa
Immediate neighbours rpsJ, rplD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RplC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RplC expression.png















Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01160

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: RplC binding to the precursor 23S rRNA stimulates MrnC activity PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
    • SigA two promoters, about 140bp and 200bp upstream of the start codon PubMed
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed