Difference between revisions of "AcuA"
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| − | * '''Description:''' protein acetylase for the control of AcsA activity <br/><br/> | + | * '''Description:''' protein acetylase for the control of [[AcsA]] activity <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || Gcn5-related N-acetyltransferase | |style="background:#ABCDEF;" align="center"| '''Product''' || Gcn5-related N-acetyltransferase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of AcsA activity | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[AcsA]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 5.028 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 24 kDa, 5.028 | ||
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[acuA]]-[[acuB]]-[[acuC]]'' {{PubMed|7934817}} | ||
| − | * ''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7913927}} |
| − | * '''[[ | + | * '''Regulation:''' |
| + | ** repressed by glucose (3.4-fold) ([[CcpA]]) {{PubMed|7913927,12850135}} | ||
| − | * ''' | + | * '''Regulatory mechanism:''' |
| − | + | ** [[CcpA]]: transcription repression {{PubMed|7913927}} | |
| − | * | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 12:38, 19 December 2009
- Description: protein acetylase for the control of AcsA activity
| Gene name | acuA |
| Synonyms | |
| Essential | no |
| Product | Gcn5-related N-acetyltransferase |
| Function | control of AcsA activity |
| MW, pI | 24 kDa, 5.028 |
| Gene length, protein length | 630 bp, 210 aa |
| Immediate neighbours | acsA, acuB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: acetylates (and thereby inactivates) AcsA on Lys-549 PubMed PubMed
- Protein family: acetyltransferase family (according to Swiss-Prot) Gcn5-relatedN-acetyltransferase PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P39065
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
