Difference between revisions of "SrfAD"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[srfAA]]-[[srfAB]]-[[comS]]-[[srfAC]]-[[srfAD]]'' {{PubMed|1715856}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1715856}} |
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8830686 PubMed] | ** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8830686 PubMed] | ||
| + | ** repressed during hydrogen peroxide stress ([[PerR]]) {{PubMed|16166527}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/8830686 PubMed] | ** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/8830686 PubMed] | ||
| + | ** [[ComA]]: transcription activation {{PubMed|1715856}} | ||
| + | ** [[PerR]]: transcription activation {{PubMed|16166527}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
| Line 120: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>18704089,16166527,17227471, 17190806,8830686, </pubmed> | + | <pubmed>18704089,16166527,17227471, 17190806,8830686, 1715856</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 18:47, 19 August 2009
- Description: surfactin synthetase / competence
| Gene name | srfAD |
| Synonyms | comL |
| Essential | no |
| Product | surfactin synthetase / competence |
| Function | antibiotic synthesis |
| MW, pI | 27 kDa, 5.22 |
| Gene length, protein length | 726 bp, 242 aa |
| Immediate neighbours | srfAC, ycxA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU03520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: thioesterase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: Q08788
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
