Difference between revisions of "ResC"
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| − | * '''Description:''' | + | * '''Description:''' part of heam translocase, required for cytochrome c synthesis <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || part of the [[ResB]]-[[ResC]] haem translocase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || cytochrome c biogenesis | |style="background:#ABCDEF;" align="center"|'''Function''' || cytochrome c biogenesis | ||
| Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' haem-binding protein, translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane {{PubMed|19682263}} |
* '''Protein family:''' ccmF/cycK/ccl1/nrfE/ccsA family (according to Swiss-Prot) | * '''Protein family:''' ccmF/cycK/ccl1/nrfE/ccsA family (according to Swiss-Prot) | ||
| Line 72: | Line 72: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[ResB]]-[[ResC]] {{PubMed|19682263}} |
| − | * '''Localization:''' | + | * '''Localization:''' cytoplasma membrane {{PubMed|19682263}} |
=== Database entries === | === Database entries === | ||
| Line 124: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>10844653, | + | <pubmed>10844653, 19682263, 8631715,11222591,9988472, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:54, 18 August 2009
- Description: part of heam translocase, required for cytochrome c synthesis
| Gene name | resC |
| Synonyms | ypxC |
| Essential | yes PubMed |
| Product | part of the ResB-ResC haem translocase |
| Function | cytochrome c biogenesis |
| MW, pI | 39 kDa, 9.564 |
| Gene length, protein length | 1056 bp, 352 aa |
| Immediate neighbours | resD, resB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU23130
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: haem-binding protein, translocation of haem from the cytoplasmic to the extracytoplasmic site of the membrane PubMed
- Protein family: ccmF/cycK/ccl1/nrfE/ccsA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasma membrane PubMed
Database entries
- Structure:
- UniProt: P35162
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Umesh Ahuja, Peter Kjelgaard, Benjamin L Schulz, Linda Thöny-Meyer, Lars Hederstedt
Haem-delivery proteins in cytochrome c maturation System II.
Mol Microbiol: 2009, 73(6);1058-71
[PubMed:19682263]
[WorldCat.org]
[DOI]
(I p)
M M Nakano, Y Zhu
Involvement of ResE phosphatase activity in down-regulation of ResD-controlled genes in Bacillus subtilis during aerobic growth.
J Bacteriol: 2001, 183(6);1938-44
[PubMed:11222591]
[WorldCat.org]
[DOI]
(P p)
N E Le Brun, J Bengtsson, L Hederstedt
Genes required for cytochrome c synthesis in Bacillus subtilis.
Mol Microbiol: 2000, 36(3);638-50
[PubMed:10844653]
[WorldCat.org]
[DOI]
(P p)
S M Birkey, W Liu, X Zhang, M F Duggan, F M Hulett
Pho signal transduction network reveals direct transcriptional regulation of one two-component system by another two-component regulator: Bacillus subtilis PhoP directly regulates production of ResD.
Mol Microbiol: 1998, 30(5);943-53
[PubMed:9988472]
[WorldCat.org]
[DOI]
(P p)
G Sun, E Sharkova, R Chesnut, S Birkey, M F Duggan, A Sorokin, P Pujic, S D Ehrlich, F M Hulett
Regulators of aerobic and anaerobic respiration in Bacillus subtilis.
J Bacteriol: 1996, 178(5);1374-85
[PubMed:8631715]
[WorldCat.org]
[DOI]
(P p)
