Iron metabolism

Parent categories	2. Metabolism 2.6. Additional metabolic pathways
Neighbouring categories	2.6.1. Biosynthesis of cell wall components 2.6.2. Biosynthesis of cofactors 2.6.3. Phosphate metabolism 2.6.4. Sulfur metabolism 2.6.5. Iron metabolism 2.6.6. Miscellaneous metabolic pathways
Related categories	Acquisition of iron Fur regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

• Note: the main systems for iron uptake in B. subtilis 168 are YfmF-YfmD-YfmE-YfmC-YhfQ and EfeO-EfeU with EfeB PubMed

ABC transporters for theuptake of iron/ siderophores

• YusV-FeuB-FeuC-FeuA: uptake of the siderophores enterobactin and bacillibactin
• FhuC-FhuB-FhuG-FhuD-YxeB: uptake of ferrichrome und ferrioxamine
• YclN-YclO-YclP-YclQ: uptake of petrobactin (a siderophore produced by B. anthracis and B. cereus)
• YusV-YfiZ-YfhA-YfiY: uptake of the siderophores schizokinen and arthrobactin
• YfmF-YfmD-YfmE-YfmC-YhfQ: uptake of iron/citrate

Elemental iron transport system

• EfeO-EfeU, EfeB

Acquisition of iron/other

• besA
• btr
• cypX
• dhbA
• dhbB
• dhbC
• dhbE
• dhbF
• dps
• fbpA
• fbpB
• fbpC
• fsrA
• fur
• mrgA
• ybbA
• yhfQ
• ymfD
• yvmB
• yvmC

Acquisition of iron/ based on similarity

• ytoA
• yvrA
• yvrB
• yvrC

Export of Fe(II)

• pfeT

Biosynthesis of iron-sulfur clusters

• fra
• sufA
• sufB
• sufC
• sufD
• sufS
• sufU
• yitW

Important original publications

Emily M Roy, Kevin L Griffith
Characterization of a Novel Iron Acquisition Activity That Coordinates the Iron Response with Population Density under Iron-Replete Conditions in Bacillus subtilis.
J Bacteriol: 2017, 199(1);
[PubMed:27795321] [WorldCat.org] [DOI] (I e)