YciB

• Description: zinc transporter
  
  

Gene name	yciB
Synonyms
Essential	no
Product	zinc transporter
Function	zinc uptake
Gene expression levels in SubtiExpress: yciB
Metabolic function and regulation of this protein in SubtiPathways: yciB
MW, pI	21 kDa, 6.18
Gene length, protein length	582 bp, 194 aa
Immediate neighbours	yciA, yczL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

Zur regulon

The gene

Basic information

• Locus tag: BSU03350

Database entries

• BsubCyc: BSU03350

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: lipoprotein, cell membrane at the cell poles PubMed

Database entries

• BsubCyc: BSU03350

• Structure:

• UniProt: C0SP99

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yciA-yciB-yciC PubMed

• Expression browser: yciB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by zinc starvation (Zur) PubMed

• Regulatory mechanism:
  • Zur: transcription repression in the presence of zinc PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Marc Bramkamp
The putative Bacillus subtilis L,D-transpeptidase YciB is a lipoprotein that localizes to the cell poles in a divisome-dependent manner.
Arch Microbiol: 2010, 192(1);57-68
[PubMed:20013255] [WorldCat.org] [DOI] (I p)

Ahmed Gaballa, Tao Wang, Rick W Ye, John D Helmann
Functional analysis of the Bacillus subtilis Zur regulon.
J Bacteriol: 2002, 184(23);6508-14
[PubMed:12426338] [WorldCat.org] [DOI] (P p)

A Gaballa, J D Helmann
Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.
J Bacteriol: 1998, 180(22);5815-21
[PubMed:9811636] [WorldCat.org] [DOI] (P p)