Ribosome

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Most genes encoding ribosomal proteins are essential and many ribosomal proteins belong to the small set of universally conserved proteins.

Structure of the ribosome

Proteins of the large subunit

Proteins of the small subunit

Proteins that are part of the ribosome only under specific conditions

  • Ctc: present in the large subunit under stress conditions
  • RpmGC: replaces L33 under conditions of zinc limitation
  • YbxF: L7 family, associated to the ribosome during logarithmic growth
  • YhzA: replaces L31 under conditions of zinc limitation
  • YtiA: replaces S14 under conditions of zinc limitation

Proteins that are similar to ribosomal proteins

Related pages

Back to Protein-protein interactions

Important original publications

Lars V Bock, Christian Blau, Gunnar F Schröder, Iakov I Davydov, Niels Fischer, Holger Stark, Marina V Rodnina, Andrea C Vaiana, Helmut Grubmüller
Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat Struct Mol Biol: 2013, 20(12);1390-6
[PubMed:24186064] [WorldCat.org] [DOI] (I p)

Ningning Li, Yuling Chen, Qiang Guo, Yixiao Zhang, Yi Yuan, Chengying Ma, Haiteng Deng, Jianlin Lei, Ning Gao
Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit.
Nucleic Acids Res: 2013, 41(14);7073-83
[PubMed:23700310] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Nico Pietack, Jörg Stülke
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
Mol Biosyst: 2013, 9(6);1068-75
[PubMed:23420519] [WorldCat.org] [DOI] (I p)

Genki Akanuma, Hideaki Nanamiya, Yousuke Natori, Koichi Yano, Shota Suzuki, Shuya Omata, Morio Ishizuka, Yasuhiko Sekine, Fujio Kawamura
Inactivation of ribosomal protein genes in Bacillus subtilis reveals importance of each ribosomal protein for cell proliferation and cell differentiation.
J Bacteriol: 2012, 194(22);6282-91
[PubMed:23002217] [WorldCat.org] [DOI] (I p)

Alex Rosenberg, Lior Sinai, Yoav Smith, Sigal Ben-Yehuda
Dynamic expression of the translational machinery during Bacillus subtilis life cycle at a single cell level.
PLoS One: 2012, 7(7);e41921
[PubMed:22848659] [WorldCat.org] [DOI] (I p)


Reviews on ribosome structure and function