SpoIVB
- Description: serine protease, cleaves SpoIVFA to prepare it for CtpB cleavage, this results in pro-SigK processing/activation in the mother-cell, does also cleave CtpB
| Gene name | spoIVB |
| Synonyms | |
| Essential | no |
| Product | serine protease |
| Function | control of SigK activation |
| Gene expression levels in SubtiExpress: spoIVB | |
| Interactions involving this protein in SubtInteract: SpoIVB | |
| MW, pI | 45 kDa, 8.842 |
| Gene length, protein length | 1275 bp, 425 aa |
| Immediate neighbours | spo0A, recN |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24230
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot)
- Protein family: PDZ protease PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Effectors of protein activity:
- Localization:
- intracellular space between the mother cell and the forespore PubMed
Database entries
- Structure:
- UniProt: P17896
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: spoIVB PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Simon Cutting, London, UK homepage
Your additional remarks
References
