CwlO
- Description: D,L-endopeptidase-type autolysin, primary autolytic pathway for cell elongation
Gene name | cwlO |
Synonyms | yzkA, yvcE |
Essential | no |
Product | endopeptidase-type autolysin |
Function | cell wall synthesis, cell proliferation |
Gene expression levels in SubtiExpress: cwlO | |
MW, pI | 50 kDa, 5.326 |
Gene length, protein length | 1419 bp, 473 aa |
Immediate neighbours | trxB, yvcD |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
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Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell wall synthesis, cell wall degradation/ turnover
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34800
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase C40 family (according to Swiss-Prot)
- Paralogous protein(s): the C-terminal D,L-endopeptidase domains of LytE, LytF, CwlS, and CwlO exhibit strong sequence similarity
Extended information on the protein
- Kinetic information:
- Domains:
- C-terminal D,L-endopeptidase domain PubMed
- Modification:
- Cofactor(s):
Database entries
- Structure:
- UniProt: P40767
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
- The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications