BofC

• Description: general stress protein, controls processing of pro-SigK by SpoIVFB
  
  

Gene name	bofC
Synonyms
Essential	no
Product	forespore regulator of the sigma-K checkpoint
Function	control of processing of pro-SigK by SpoIVFB
Gene expression levels in SubtiExpress: bofC
Interactions involving this protein in SubtInteract: BofC
MW, pI	19 kDa, 5.753
Gene length, protein length	510 bp, 170 aa
Immediate neighbours	ruvA, csbX
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control, sporulation proteins, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon, SigF regulon, SigG regulon

The gene

Basic information

• Locus tag: BSU27750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • BofC-SpoIVB PubMed

• Localization:

Database entries

• Structure: 2BW2

• UniProt: O05391

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csbX-bofC PubMed

• Expression browser: bofC PubMed

• Sigma factor: SigF PubMed, SigG PubMed, SigB PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigF, SigG) PubMed
  • induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: