IolR

• Description: transcriptional repressor of the iol operon, DeoR family
  
  

Gene name	iolR
Synonyms
Essential	no
Product	transcriptional repressor
Function	regulation of myo-inositol catabolism
Gene expression levels in SubtiExpress: iolR
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	28 kDa, 6.331
Gene length, protein length	753 bp, 251 aa
Immediate neighbours	iolA, iolS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

IolR regulon

The gene

Basic information

• Locus tag: BSU39770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: inducer: 2-deoxy-5-keto-D-gluconic acid-6-phosphate

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P46337

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: iolR-iolS PubMed

• Expression browser: iolR PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by inositol (IolR) PubMed

• Regulatory mechanism:
  • IolR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Yasutaro Fujita, University of Fukuyama, Japan
• Ken-ichi Yoshida, Kobe University, Japan