YtvA

• Description: blue light sensor, positive regulation of SigB activity under conditions of blue light
  
  

Gene name	ytvA
Synonyms
Essential	no
Product	blue light receptor, flavoprotein
Function	control of SigB activity
Gene expression levels in SubtiExpress: ytvA
MW, pI	29 kDa, 4.69
Gene length, protein length	783 bp, 261 aa
Immediate neighbours	ytvB, yttB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sigma factors and their control

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

• Locus tag: BSU30340

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): RsbR, RsbRB, RsbRC, RsbRD, YtvA

Extended information on the protein

• Kinetic information:

• Domains: LOV domain, STAS domain

• Modification:

• Cofactor(s): FMN

• Effectors of protein activity:
  • YtvA-dependent light activation of the SigB stress response is positively and negatively regulated by RsbRA and RsbRB, respectively PubMed

• Interactions:
  • forms dimers PubMed
  • YtvA-RsbRA PubMed
  • YtvA-RsbRD PubMed

• Localization:

Database entries

• Structure: 2PR5 (dark), 2PR6 (light)

• UniProt: O34627

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ytvA PubMed

• Sigma factor:

• Regulation:
  • induced under conditions of disulfide stress (Spx) PubMed

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A965 ( ytvA::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Chet Price, Davis, USA homepage

References

Reviews

Additional reviews: PubMed

Original publications

Additional publications: PubMed