YtiA

• Description: general stress protein, binds in the stationary phase to the ribosome, replaces RpmE under conditions of zinc limitation
  
  

Gene name	ytiA
Synonyms	rpmE2, rpmEB
Essential	no
Product	accessory ribosomal protein
Function	survival of salt stress
Gene expression levels in SubtiExpress: ytiA
Interactions involving this protein in SubtInteract: YtiA
MW, pI	9 kDa, 9.808
Gene length, protein length	246 bp, 82 aa
Immediate neighbours	ytiB, ythA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, general stress proteins (controlled by SigB), phosphoproteins

This gene is a member of the following regulons

SigB regulon, Zur regulon

The gene

Basic information

• Locus tag: BSU30700

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Type B subfamily (according to Swiss-Prot)

• Paralogous protein(s): RpmE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-70 PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34967

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: ytiA PubMed

• Expression browser: ytiA PubMed

• Sigma factor: SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • induced by zinc starvation (Zur) PubMed

• Regulatory mechanism:
  • Zur: transcription repression in the presence of zinc PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: