TagA

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  • Description: UDP-N-acetyl-D-mannosamine transferase

Gene name tagA
Synonyms
Essential yes PubMed, no PubMed
Product UDP-N-acetyl-D-mannosamine transferase
Function biosynthesis of teichoic acid
MW, pI 29 kDa, 10.133
Gene length, protein length 768 bp, 256 aa
Immediate neighbours tagD, tagB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TagA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TagA expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

PhoP regulon, WalR regulon

The gene

Basic information

  • Locus tag: BSU35750

Phenotypes of a mutant

  • essential PubMed, reduced growth rate, loss of rod-like morphology PubMed
  • inactivation of tagA strongly restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-N-acetyl-D-mannosamine + N-acetyl-D-glucosaminyldiphosphoundecaprenol = UDP + N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol (according to Swiss-Prot)
  • Protein family: glycosyltransferase 26 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • repressed when phosphate is available (PhoP) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed