YaaJ
- Description: tRNA specific adenosine deaminase
| Gene name | yaaJ |
| Synonyms | |
| Essential | no |
| Product | tRNA specific adenosine deaminase |
| Function | tRNA modification |
| MW, pI | 17 kDa, 5.636 |
| Gene length, protein length | 483 bp, 161 aa |
| Immediate neighbours | yaaI, scr |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00180
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: cytidine and deoxycytidylate deaminase family (according to Swiss-Prot)
- Paralogous protein(s):
- The corresponding gene in E. coli: EcoliWiki
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: P21335
- KEGG entry: [3]
- E.C. number: 3.5.4.-
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Takashi Inaoka, Takenori Satomura, Yasutaro Fujita, Kozo Ochi
Novel gene regulation mediated by overproduction of secondary metabolite neotrehalosadiamine in Bacillus subtilis.
FEMS Microbiol Lett: 2009, 291(2);151-6
[PubMed:19087206]
[WorldCat.org]
[DOI]
(I p)
Heather C Losey, Alexander J Ruthenburg, Gregory L Verdine
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
Nat Struct Mol Biol: 2006, 13(2);153-9
[PubMed:16415880]
[WorldCat.org]
[DOI]
(P p)
Jeannette Wolf, André P Gerber, Walter Keller
tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli.
EMBO J: 2002, 21(14);3841-51
[PubMed:12110595]
[WorldCat.org]
[DOI]
(P p)
