TxpA

• Description: toxic peptide
  
  

Gene name	txpA
Synonyms	yqcR, yqdB
Essential	no
Product	toxic peptide
Function	toxin
MW, pI	6 kDa, 8.139
Gene length, protein length	177 bp, 59 aa
Immediate neighbours	yqbN, ratA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, Skin element, membrane proteins

This gene is a member of the following regulons

ratA regulon

The gene

Basic information

• Locus tag: BSU26050

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane

Database entries

• Structure:

• UniProt: P54373

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: txpA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism: expression is prevented by the ratA antisense RNA PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Richard Losick, Harvard University, Cambridge, USA Homepage

References

Jessica M Silvaggi, John B Perkins, Richard Losick
Small untranslated RNA antitoxin in Bacillus subtilis.
J Bacteriol: 2005, 187(19);6641-50
[PubMed:16166525] [WorldCat.org] [DOI] (P p)