TagU

• Description: negative regulator for lytA-lytB-lytC and lytR expression
  
  

Gene name	lytR
Synonyms
Essential	no
Product	negative regulator for lytA-lytB-lytC and lytR expression
Function	regulation of cell separation and autolysis
MW, pI	34 kDa, 9.527
Gene length, protein length	918 bp, 306 aa
Immediate neighbours	lytA, mnaA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell wall degradation/ turnover, transcription factors and their control, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins

This gene is a member of the following regulons

LytR regulon, SigX regulon

The LytR regulon:

• lytA-lytB-lytC, lytR

The gene

Basic information

• Locus tag: BSU35650

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: lytR/cpsA/psr regulatory protein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q02115

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lytR PubMed

• Sigma factor: SigA PubMed, SigX PubMed

• Regulation:

• Regulatory mechanism:
  • LytR: autorepression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: