OpuCC

• Description: glycine betaine/carnitine/choline ABC transporter (binding protein)
  
  

Gene name	opuCC
Synonyms	yvbC
Essential	no
Product	glycine betaine/carnitine/choline ABC transporter (binding protein)
Function	compatible solute transport
Metabolic function and regulation of this protein in SubtiPathways: Stress
MW, pI	33 kDa, 5.694
Gene length, protein length	909 bp, 303 aa
Immediate neighbours	opuCD, opuCB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, coping with hyper-osmotic stress, membrane proteins

The gene

Basic information

• Locus tag: BSU33810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): OpuBC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: OpuCA-(OpuCB-OpuCD)-OpuCC PubMed

• Localization:
  • associated to the membrane (via OpuCB-OpuCD) PubMed
  • lipoprotein PubMed

Database entries

• Structure:

• UniProt: O32243

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: opuCA-opuCB-opuCC-opuCD PubMed

• Sigma factor:

• Regulation:
  • induced by salt stress PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

R M Kappes, B Kempf, S Kneip, J Boch, J Gade, J Meier-Wagner, E Bremer
Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.
Mol Microbiol: 1999, 32(1);203-16
[PubMed:10216873] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

G Nau-Wagner, J Boch, Le Good JA, E Bremer
High-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis.
Appl Environ Microbiol: 1999, 65(2);560-8
[PubMed:9925583] [WorldCat.org] [DOI] (P p)