SdpR

• Description: transcriptional repressor of the sdpR-sdpI operon
  
  

Gene name	sdpR
Synonyms	yvbA
Essential	no
Product	transcriptional regulator (ArsR family)
Function	regulation of protection against SdpC
MW, pI	10 kDa, 7.328
Gene length, protein length	270 bp, 90 aa
Immediate neighbours	sdpI, opuCD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33790

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

transcription factors and their control, toxins, antitoxins and immunity against toxins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: SdpI binds and sequesters SdpR if extracellular SdpC is present, this results in induction of the sdpR-sdpI operon PubMed

• Interactions: SdpI-SdpR PubMed

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O32242

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sdpR-sdpI PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed during logrithmic growth (AbrB) PubMed
  • induced by extracellular SdpC (SdpR) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • SdpR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: