MmgE

---

---

This Page Is Currently Under Construction And Will Be Available Shortly, Please Visit Reserve Copy Page

---

CLICK HERE

---

• Description: putative methyl-cis-aconitase <br/><br/>

Gene name	mmgE
Synonyms	yqiP, prpD
Essential	no
Product	unknown
Function	mother cell metabolism
Metabolic function and regulation of this protein in SubtiPathways: <br/>Central C-metabolism
MW, pI	52 kDa, 6.111
Gene length, protein length	1416 bp, 472 aa
Immediate neighbours	yqiQ, mmgD
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> <div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

• Locus tag: BSU24130

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H₂O (according to Swiss-Prot)

• Protein family: prpD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P45859

• KEGG entry: [3]

• E.C. number: 4.2.1.79

Expression and regulation

• Operon: mmgA-mmgB-mmgC-mmgD-mmgE-yqiQ PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>8759838,15699190,, </pubmed>