TagB

• Description: putative CDP-glycerol:glycerol phosphate glycerophosphotransferase
  
  

Gene name	tagB
Synonyms
Essential	yes PubMed
Product	putative CDP-glycerol:glycerol phosphate glycerophosphotransferase
Function	biosynthesis of teichoic acid
MW, pI	44 kDa, 8.925
Gene length, protein length	1143 bp, 381 aa
Immediate neighbours	tagA, tagC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35760

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: CDP-glycerol + ManNAc-GlcNAc-PP-undecaprenol = CMP + Gro-P-ManNAc-GlcNAc-PP-undecaprenol (according to Swiss-Prot)

• Protein family: CDP-glycerol glycerophosphotransferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P27621

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tagA-tagB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed when phosphate is available (PhoP) PubMed

• Regulatory mechanism:
  • PhoP: transcription repression PubMed
  • WalR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: