ThyB

• Description: thymidylate synthase B
  
  

Gene name	thyB
Synonyms
Essential	no
Product	thymidylate synthase B
Function	biosynthesis of thymidine nucleotides
MW, pI	30 kDa, 6.272
Gene length, protein length	792 bp, 264 aa
Immediate neighbours	dfrA, ypjQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: DfrA-ThyB

• Localization:

Database entries

• Structure:

• Swiss prot entry: P11044

• KEGG entry: BSU21820

• E.C. number: 2.1.1.45

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed