TrpD

• Description: anthranilate phosphoribosyltransferase
  
  

Gene name	trpD
Synonyms
Essential	no
Product	anthranilate phosphoribosyltransferase
Function	biosynthesis of tryptophan
MW, pI	35 kDa, 4.904
Gene length, protein length	1014 bp, 338 aa
Immediate neighbours	trpC, trpE
Gene sequence (+200bp)	Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: trpE-trpD-trpC-trpF-trpB-trpA

• Sigma factor: SigA

• Regulation: induction by tryptophan ( TRAP)

• Regulatory mechanism: TRAP: binding to the mRNA in the presence of tryptophan, this results in transcription termination

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed