YbfO

• Description: similar to erythromycin esterase
  
  

Gene name	ybfO
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ybfO
MW, pI	51 kDa, 6.678
Gene length, protein length	1338 bp, 446 aa
Immediate neighbours	ybfN, ybfP
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell envelope stress proteins (controlled by SigM, V, W, X, Y), resistance against toxins/ antibiotics

This gene is a member of the following regulons

AbrB regulon, SigW regulon, Efp-dependent proteins

The gene

Basic information

• Locus tag: BSU02310

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • extracellular (signal peptide) PubMed

Database entries

• Structure:

• UniProt: O31455

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ybfO (according to DBTBS)
  • ybfO-ybfP PubMed
  • ybfO-ybfP-ybfQ PubMed

• Expression browser: ybfO PubMed

• Sigma factor: SigW PubMed

• Regulation:
  • strongly induced by alkali shock (SigW PubMed)
  • repressed during logarithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:
  • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional references: PubMed