CapE

• Description: stimulates poly-gamma-glutamate production in the presence of zinc, also involved in extra-chromosomal DNA maintenance
  
  

Gene name	capE
Synonyms	ywtC, pgsE, edmS
Essential	no
Product	unknown
Function	capsule synthesis
Gene expression levels in SubtiExpress: capE
MW, pI	6 kDa, 6.487
Gene length, protein length	165 bp, 55 aa
Immediate neighbours	pgdS, capA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

capsule biosynthesis and degradation, membrane proteins

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

• Locus tag: BSU35870

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • stimulates poly-gamma-glutamate production in the presence of zinc PubMed
  • also involved in extra-chromosomal DNA maintenance PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: N-terminal membrane-anchoring domain and a C-terminal assembly accelerator-like structure PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: P96739

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: capB-capC-capA-capE PubMed

• Expression browser: capE PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism: activated by DegU-P PubMed

• Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: