SpoVK

• Description: required for spore maturation
  
  

Gene name	spoVK
Synonyms	spoVJ
Essential	no
Product	unknown
Function	spore maturation
Gene expression levels in SubtiExpress: spoVK
MW, pI	36 kDa, 8.825
Gene length, protein length	966 bp, 322 aa
Immediate neighbours	cwlC, ynbA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU17420

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cbxX/cfxQ family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P27643

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVK PubMed

• Expression browser: spoVK PubMed

• Sigma factor: SigE PubMed, SigK PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE, SigK) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S99 ( spoVK::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

N Fan, S Cutting, R Losick
Characterization of the Bacillus subtilis sporulation gene spoVK.
J Bacteriol: 1992, 174(3);1053-4
[PubMed:1732196] [WorldCat.org] [DOI] (P p)

D Foulger, J Errington
Sequential activation of dual promoters by different sigma factors maintains spoVJ expression during successive developmental stages of Bacillus subtilis.
Mol Microbiol: 1991, 5(6);1363-73
[PubMed:1787791] [WorldCat.org] [DOI] (P p)

J Errington, L Wootten, J C Dunkerley, D Foulger
Differential gene expression during sporulation in Bacillus subtilis: regulation of the spoVJ gene.
Mol Microbiol: 1989, 3(8);1053-60
[PubMed:2514336] [WorldCat.org] [DOI] (P p)