spoVK

spoVK
168

required for spore maturation, acts as a chaperone to activate the peptidoglycan glycosyltransferase MurG during sporulation

Locus
BSU_17420
Molecular weight
36.52 kDa
Isoelectric point
8.82
Protein length
322 aaSequenceBlast
Gene length
969 bpSequenceBlast
Function
spore maturation
Product
AAA+ ATPase chaperone
Essential
no
Synonyms
spoVK, spoVJ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0464 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,874,203  1,875,171
The protein
Catalyzed reaction/ biological activity
interacts with and promotes MurG peptidoglycan glycosyltransferase activity during sporulation PubMed
has ATPase activity: ATP + H2O --> ADP + H+ + phosphate PubMed
Protein family
cbxX/cfxQ family (single member, according to UniProt)
Structure
3ZUH (PDB) (from Rhodobacter sphaeroides, 41% identity) PubMed
P27643 (AlphaFold)
Localization
forespore PubMed
Expression and Regulation
Operons
Genes
spoVK
Description
PubMed
Regulation
expressed during sporulation in the mother cell (SigE, SigK) PubMed
Regulatory mechanism
SpoIIID: activation, PubMed, in spoIIID regulon
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
SigK: sigma factor, PubMed, in sigK regulon
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spoVK

2025-03-16 06:06:15

ghost

51

514217a999ec57d4a9e0cdf976b1ebb4cdfdae0d

8696C5A04C3660A4EF40EDDA10FAE063D55B2315

Biological materials
Mutant
1S99 ( spoVK::erm), PubMed, available at BGSC
BKE17420 (spoVK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTCACCTCTCTGTTCT,  downstream forward: _UP4_TAGACCTCTCAGTTTTTGAG
BKK17420 (spoVK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCTTCACCTCTCTGTTCT,  downstream forward: _UP4_TAGACCTCTCAGTTTTTGAG
References
Reviews
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Original Publications
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69D4685E435B472A3E87E312ECA77553631687E4

Page visits: 2834

Time of last update: 2025-04-02 03:53:35

Author of last update: Jstuelk