Dck

• Description: deoxyadenosin/deoxycytidine kinase
  
  

Gene name	dck
Synonyms	yaaF
Essential	no
Product	deoxyadenosin/deoxycytidine kinase
Function	purine salvage and interconversion
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation)
MW, pI	25 kDa, 5.536
Gene length, protein length	651 bp, 217 aa
Immediate neighbours	trnSL-Ser1, dgk
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

The gene

Basic information

• Locus tag: BSU00140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P37529

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: dgk-dck

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

R B Andersen, J Neuhard
Deoxynucleoside kinases encoded by the yaaG and yaaF genes of Bacillus subtilis. Substrate specificity and kinetic analysis of deoxyguanosine kinase with UTP as the preferred phosphate donor.
J Biol Chem: 2001, 276(8);5518-24
[PubMed:11078735] [WorldCat.org] [DOI] (P p)

H Møllgaard
Deoxyadenosine/deoxycytidine kinase from Bacillus subtilis. Purification, characterization, and physiological function.
J Biol Chem: 1980, 255(17);8216-20
[PubMed:6251049] [WorldCat.org] (P p)