dck

dck
168

deoxyadenosin/deoxycytidine kinase

Locus
BSU_00140
Molecular weight
25.30 kDa
Isoelectric point
5.54
Protein length
217 aaSequenceBlast
Gene length
654 bpSequenceBlast
Function
purine salvage and interconversion
Product
deoxyadenosin/deoxycytidine kinase
Essential
no
Synonyms
dck, yaaF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1428 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
22,496 → 23,149
The protein
Catalyzed reaction/ biological activity
ATP + deoxyadenosine --> ADP + dAMP (accoding to UniProt)
NTP + deoxycytidine --> NDP + dCMP (accoding to UniProt)
Protein family
DCK/DGK family (together woth Dgk) (accoding to UniProt)
Structure
8PUU (PDB) (from Giardia intestinalis , 39.8% identity)
P37529 (AlphaFold)
Paralogous protein(s)
Dgk
Localization
cytoplasm (accoding to UniProt)
Expression and Regulation
Operons
Genes
dgk-dck
Description
PubMed
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dgk→dck

2025-04-01 21:54:53

Jstuelk

93

a79e3573c7ef40ce7edc240f2c862e5e075bc687

5B80CB1DA13607F688D45E84AA89AAB4A93774D1

Biological materials
Mutant
MGNA-B887 (yaaF::erm), available at the NBRP B. subtilis, Japan
BKE00140 (Δdck::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCTTAGGGATATGATGTT,  downstream forward: _UP4_TGAATCTCAGTCGAGATTCA
BKK00140 (Δdck::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATTCTTAGGGATATGATGTT,  downstream forward: _UP4_TGAATCTCAGTCGAGATTCA
References
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Time of last update: 2025-04-01 09:11:00

Author of last update: Jstuelk