TetB

• Description: multifunctional tetracycline/Na+ resistance protein
  
  

Gene name	tetB
Synonyms	tetA, tetA(L)
Essential	no
Product	multifunctional tetracycline/Na+ resistance protein
Function	resistance to tetracyclin
MW, pI	49 kDa, 9.537
Gene length, protein length	1374 bp, 458 aa
Immediate neighbours	yyaP, tetL
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, resistance against toxins/ antibiotics, membrane proteins

The gene

Basic information

• Locus tag: BSU40770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: TCR/tet family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P23054

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tetL-tetB (according to DBTBS)

• Expression browser: tetB PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage