QcrA

• Description: menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit), component of the cytochrome bc complex
  
  

Gene name	qcrA
Synonyms	bfcA, petC
Essential	no
Product	menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit)
Function	respiration
MW, pI	18 kDa, 6.078
Gene length, protein length	501 bp, 167 aa
Immediate neighbours	qcrB, ypiF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, ResD regulon

The gene

Basic information

• Locus tag: BSU22560

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: accD/PCCB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P46911

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: qcrA-qcrB-qcrC PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by casamino acids PubMed
  • induced by oxygen limitation (ResD) PubMed
  • repressed by glucose (5.5-fold) (CcpA) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed
  • CcpA: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed