YbfK

From SubtiWiki
Revision as of 09:58, 18 January 2012 by Jstuelk (talk | contribs)
Jump to: navigation, search
  • Description: carboxylesterase NP

Gene name ybfK
Synonyms cesB
Essential no
Product carboxylesterase NP
Function degradation of isoprenoid-containing lipids
MW, pI 32 kDa, 5.135
Gene length, protein length 888 bp, 296 aa
Immediate neighbours ybfJ, pssA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbfK context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02260

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A carboxylic ester + H2O = an alcohol + a carboxylate (according to Swiss-Prot)
  • Protein family: AB hydrolase superfamily (according to Swiss-Prot)
  • Paralogous protein(s): Nap

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 2R11 (the structure of Nap, 60% identity, 87% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

M J Dröge, R Bos, W J Quax
Paralogous gene analysis reveals a highly enantioselective 1,2-O-isopropylideneglycerol caprylate esterase of Bacillus subtilis.
Eur J Biochem: 2001, 268(11);3332-8
[PubMed:11389736] [WorldCat.org] [DOI] (P p)