pssA

pssA
168

phosphatidylserine synthase

Locus
BSU_02270
Molecular weight
19.47 kDa
Isoelectric point
7.88
Protein length
177 aaSequenceBlast
Gene length
534 bpSequenceBlast
Function
biosynthesis of phosphatidylethanolamine
Product
phosphatidylserine synthase
Essential
no
E.C.
2.7.8.8
Synonyms
pssA, pss
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1183 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
247,744 → 248,277
The protein
Catalyzed reaction/ biological activity
CDP-1,2-diacyl-sn-glycerol + L-serine --> 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H+ (according to UniProt)
Protein family
CDP-alcohol phosphatidyltransferase class-I family (with PgsA, according to UniProt)
Structure
P39823 (AlphaFold)
Localization
cell membrane at the septum PubMed
Expression and Regulation
Operons
Genes
ybfK-pssA-petA-psd
Description
PubMed
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigX: sigma factor, PubMed, in sigX regulon
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ybfK→psd

2025-03-26 10:19:59

Jstuelk

133

9c5c2fcf642de63f240b8ac199efc5b5939a836b

2A09CF2D25D4B824D045D3A292B8FC9B5A167361

Biological materials
Mutant
BKE02270 (ΔpssA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACAGTGTAACCAAACCTCC,  downstream forward: _UP4_GCAGAAAACCTGGAGTCTGG
BKK02270 (ΔpssA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACAGTGTAACCAAACCTCC,  downstream forward: _UP4_GCAGAAAACCTGGAGTCTGG
References
Reviews
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Original Publications
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DE49797486CEC172F912D26A6BF2223190BF5DAD

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Time of last update: 2025-04-02 04:49:00

Author of last update: Jstuelk