Fbp

• Description: fructose-1,6-bisphosphatase, involved in gluconeogenesis
  
  

Gene name	fbp
Synonyms	fdp, yydE
Essential	no
Product	fructose-1,6-bisphosphatase
Function	gluconeogenesis
Gene expression levels in SubtiExpress: fbp
Metabolic function and regulation of this protein in SubtiPathways: fbp
MW, pI	77 kDa, 5.601
Gene length, protein length	2013 bp, 671 aa
Immediate neighbours	yydF, yydD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

carbon core metabolism

The gene

Basic information

• Locus tag: BSU40190

Database entries

• BsubCyc: BSU40190

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate + H₂O = D-fructose 6-phosphate + phosphate (according to Swiss-Prot)

• Protein family: FBPase class 3 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:
  • specific activity: 0.203 µmol min^-1 (mg protein)^-1 PubMed

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU40190

• Structure:

• UniProt: Q45597

• KEGG entry: [3]

• E.C. number: 3.1.3.11

Expression and regulation

• Operon: fpb PubMed

• Expression browser: fbp PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: