YlbQ

• Description: 2-dehydropantoate 2-reductase
  
  

Gene name	ylbQ
Synonyms
Essential	no
Product	2-dehydropantoate 2-reductase
Function	biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: ylbQ
MW, pI	33 kDa, 5.857
Gene length, protein length	894 bp, 298 aa
Immediate neighbours	ylbP, bshC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Spx regulon

The gene

Basic information

• Locus tag: BSU15110

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (R)-pantoate + NADP⁺ = 2-dehydropantoate + NADPH (according to Swiss-Prot)

• Protein family: ketopantoate reductase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 3LGO

• UniProt: O34661

• KEGG entry: [2]

• E.C. number: 1.1.1.169

Expression and regulation

• Operon: ylbQ-bshC PubMed

• Expression browser: ylbQ PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by diamide stess (thiol depletion) (Spx) PubMed

• Regulatory mechanism:
  • Spx: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: