GbsR

• Description: transcription repressor of the gbsA-gbsB operon
  
  

Gene name	gbsR
Synonyms	yuaC
Essential	no
Product	transcription repressor
Function	regulation of osmoprotection
MW, pI	20 kDa, 4.62
Gene length, protein length	540 bp, 180 aa
Immediate neighbours	gbsA, bslA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

miscellaneous metabolic pathways, transcription factors and their control, coping with hyper-osmotic stress

The gene

Basic information

• Locus tag: BSU31070

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • sensing of choline PubMed
  • control of the gbsA-gbsB and opuBA-opuBB-opuBC-opuBD operons PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:
  • binds the inducer choline with an apparent K(D) of approximately 165 μM PubMed

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P71015

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Erhard Bremer, University of Marburg, Germany homepage

References

Additional publications: PubMed