YqjL

• Description: general stress protein, putative hydrolase involved in oxidative stress resistance, important for survival at low temperature
  
  

Gene name	yqjL
Synonyms
Essential	no
Product	putative hydrolase
Function	resistence against paraquat
Gene expression levels in SubtiExpress: yqjL
MW, pI	28 kDa, 6.56
Gene length, protein length	759 bp, 253 aa
Immediate neighbours	yqjM, rnz
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

SigB regulon, SigM regulon, SigW regulon

The gene

Basic information

• Locus tag: BSU23830

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P54549

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yqjL (according to DBTBS)

• Expression browser: yqjL PubMed

• Sigma factor: SigB PubMed, SigM PubMed, SigW PubMed

• Regulation:
  • induced by stress (SigB, SigM, SigW) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Min Cao, Charles M Moore, John D Helmann
Bacillus subtilis paraquat resistance is directed by sigmaM, an extracytoplasmic function sigma factor, and is conferred by YqjL and BcrC.
J Bacteriol: 2005, 187(9);2948-56
[PubMed:15838020] [WorldCat.org] [DOI] (P p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Min Cao, Tao Wang, Rick Ye, John D Helmann
Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis sigma(W) and sigma(M) regulons.
Mol Microbiol: 2002, 45(5);1267-76
[PubMed:12207695] [WorldCat.org] [DOI] (P p)