CitM

• Description: Mg2+-citrate transporter
  
  

Gene name	citM
Synonyms	yflO
Essential	no
Product	Mg2+-citrate transporter
Function	citrate uptake
Gene expression levels in SubtiExpress: citM
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism, Metal ion homeostasis
MW, pI	45 kDa, 6.227
Gene length, protein length	1299 bp, 433 aa
Immediate neighbours	yflP, yflN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

CcpA regulon, CitT regulon

The gene

Basic information

• Locus tag: BSU07610

Phenotypes of a mutant

no growth with citrate as sole carbon source PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s): CitH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P55069

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: citM-yflN PubMed

• Expression browser: citM PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by citrate (CitT) PubMed
  • repressed by glucose (CcpA) PubMed

• Regulatory mechanism:
  • CitT: transcription activation PubMed
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: