FatR
- Description: transcriptional repressor of the fatR-yrhJ operon
| Gene name | fatR |
| Synonyms | yrhI, bscR |
| Essential | no |
| Product | transcriptional repressor of the fatR yrhJ operon (TetR family) |
| Function | unknown |
| MW, pI | 22 kDa, 5.621 |
| Gene length, protein length | 582 bp, 194 aa |
| Immediate neighbours | yrhJ, yrhH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU27170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O08335
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by unsaturated fatty acids (FatR)
- Regulatory mechanism: FatR: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
M C Gustafsson, C N Palmer, C R Wolf, C von Wachenfeldt
Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species.
Arch Microbiol: 2001, 176(6);459-64
[PubMed:11734890]
[WorldCat.org]
[DOI]
(P p)
T R Lee, H P Hsu, G C Shaw
Transcriptional regulation of the Bacillus subtilis bscR-CYP102A3 operon by the BscR repressor and differential induction of cytochrome CYP102A3 expression by oleic acid and palmitate.
J Biochem: 2001, 130(4);569-74
[PubMed:11574077]
[WorldCat.org]
[DOI]
(P p)
M C Gustafsson, C von Wachenfeldt
A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter.
FEMS Microbiol Lett: 2001, 199(2);197-202
[PubMed:11377867]
[WorldCat.org]
[DOI]
(P p)
