Difference between revisions of "Prs"
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|style="background:#ABCDEF;" align="center"| '''Product''' || phosphoribosylpyrophosphate synthetase | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphoribosylpyrophosphate synthetase | ||
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || phosphoribosylpyrophosphate synthesis (biosynthesis of histidine) | + | |style="background:#ABCDEF;" align="center"|'''Function''' || phosphoribosylpyrophosphate synthesis (<br/>biosynthesis of histidine) |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/histidine.html His]''' | ||
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__TOC__ | __TOC__ | ||
| − | <br/><br/> | + | <br/><br/><br/><br/><br/> |
=The gene= | =The gene= | ||
Revision as of 10:27, 18 June 2009
- Description: phosphoribosylpyrophosphate synthetase
| Gene name | prs |
| Synonyms | |
| Essential | yes PubMed |
| Product | phosphoribosylpyrophosphate synthetase |
| Function | phosphoribosylpyrophosphate synthesis ( biosynthesis of histidine) |
| Metabolic function and regulation of this protein in SubtiPathways: His | |
| MW, pI | 34 kDa, 5.895 |
| Gene length, protein length | 951 bp, 317 aa |
| Immediate neighbours | gcaD, ctc |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00510
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: ribose-phosphate pyrophosphokinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1IBS
- Swiss prot entry: P14193
- KEGG entry: [3]
- E.C. number: 2.7.6.1
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
